上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Specnuezhenide (Synonyms: 特女贞苷; (8E)-Nuezhenide) 纯度: 98.55%
Specnuezhenide ((8E)-Nuezhenide) 是从女贞子的果实中分离出来的。Specnuezhenide ((8E)-Nuezhenide) 可通过抑制 NF-κB 和 wnt/β-catenin 信号传导来抑制 IL-1β 诱导的软骨细胞炎症。Specnuezhenide ((8E)-Nuezhenide) 可在骨关节炎 (OA) 大鼠模型中发挥抗炎作用。
Specnuezhenide Chemical Structure
CAS No. : 39011-92-2
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5 mg | ¥1500 | In-stock | |
10 mg | ¥2400 | In-stock | |
25 mg | ¥3800 | In-stock | |
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100 mg | 询价 |
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Specnuezhenide 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Immunology/Inflammation Compound Library
- NF-κB Signaling Compound Library
- Stem Cell Signaling Compound Library
- Wnt/Hedgehog/Notch Compound Library
- Natural Product Library
- Anti-Aging Compound Library
- Antioxidants Compound Library
- Differentiation Inducing Compound Library
- Glycoside Compound Library
- Oxygen Sensing Compound Library
- Terpenoids Library
- Phenols Library
- Pyroptosis Compound Library
- Cytoskeleton Compound Library
- Traditional Chinese Medicine Monomer Library
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- Anti-Pancreatic Cancer Compound Library
- Anti-Blood Cancer Compound Library
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- Transcription Factor Targeted Library
- Anti-Liver Cancer Compound Library
- Anti-Colorectal Cancer Compound Library
生物活性 |
Specnuezhenide ((8E)-Nuezhenide) is isolated from the fruits of Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) exerts anti-inflammatory effects in a rat model of osteoarthritis (OA)[1]. |
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体外研究 (In Vitro) |
Specnuezhenide (0.2-5.0 μg/mL) significantly decreases the mRNA expression of VEGFA induced by CoCl2 as a dose-dependent manner in ARPE-19 cells[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
686.66 |
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Formula |
C31H42O17 |
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CAS 号 |
39011-92-2 |
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中文名称 |
特女贞苷;女贞子甙 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (364.08 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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