上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Ryanodine
Ryanodine是可渗透细胞的兰尼碱受体调节剂。 根据其浓度，Ryanodine可以刺激或抑制Ryanodine介导的Ca2+ 释放。 在Ryania speciosa中发现的有毒二萜。
Ryanodine Chemical Structure
CAS No. : 15662-33-6
| 规格 | 价格 | 是否有货 | |
|---|---|---|---|
| 1 mg | ￥6600 | 询问价格 & 货期 | |
* Please select Quantity before adding items.
| 生物活性 |
Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. |
IC50 & Target |
Ryanodine receptor[1] |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 体内研究 (In Vivo) |
Ryanodine (100-5000 nM, 30-120 mintutes) irreversibly depresses twitch and tetanic tension of both fast and slow muscle in a dose-related manner[1]. At concentrations above 250 nM, ryanodine induces a slowly developing, dose dependent contracture which could not be blocked by 5 mMCo2+[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
|||||||||
| Clinical Trial |
|
|||||||||
| 分子量 |
493.55 |
|||||||||
| Formula |
C25H35NO9 |
|||||||||
| CAS 号 |
15662-33-6 |
|||||||||
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
|||||||||
| 储存方式 |
|
|||||||||
| 参考文献 |
|