Polyporenic acid C(Synonyms: 聚孔酸C)

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Polyporenic acid C (Synonyms: 聚孔酸C) 纯度: ≥99.0%

Polyporenic acid C 是从 P. cocos 中分离出的羊毛甾烷型三萜。Polyporenic acid C 通过死亡受体介导的凋亡途径诱导细胞凋亡 (apoptosis),而无需线粒体的参与。 Polyporenic acid C 有潜力用于肺癌的研究。

Polyporenic acid C(Synonyms: 聚孔酸C)

Polyporenic acid C Chemical Structure

CAS No. : 465-18-9

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1 mg ¥1800 In-stock
5 mg ¥4600 In-stock
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Polyporenic acid C 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Apoptosis Compound Library
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Lipid Compound Library
  • Terpenoids Library
  • Traditional Chinese Medicine Monomer Library
  • Anti-Lung Cancer Compound Library

生物活性

Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. Polyporenic acid C induces cell apoptosis through the death receptor-mediated apoptotic pathway without the involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy[1].

IC50 & Target

IC50: apoptosis[1]

分子量

482.69

Formula

C31H46O4

CAS 号

465-18-9

中文名称

聚孔酸C; 聚孢酸C

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog. 2009 Jun;48(6):498-507.