上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Leelamine hydrochloride (Synonyms: 脱氢松香胺盐酸盐)
Leelamine hydrochloride 是一种从松树皮中提取的三环二萜分子。Leelamine hydrochloride 是一种大麻素 1 型 (CB1) 激动剂,也是前列腺癌细胞中 SREBP1 调节的脂肪酸/脂质合成的抑制剂,不受雄激素受体状态的影响。Leelamine hydrochloride 抑制调节脂肪酸合成的雄激素受体 (androgen receptor) 的转录活性。
Leelamine hydrochloride Chemical Structure
CAS No. : 16496-99-4
规格 | 是否有货 | ||
---|---|---|---|
5 mg | 询价 | ||
10 mg | 询价 | ||
25 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees[1]. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor, which is known to regulate fatty acid synthesis[2,3]. |
|
---|---|---|
IC50 & Target[2] |
|
|
分子量 |
321.93 |
|
Formula |
C20H32ClN |
|
CAS 号 |
16496-99-4 |
|
中文名称 |
脱氢松香胺盐酸盐 |
|
运输条件 |
Room temperature in continental US; may vary elsewhere. |
|
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
|
参考文献 |
|