Rosiridin(Synonyms: 络塞定)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Rosiridin (Synonyms: 络塞定)

Rosiridin 可抑制 MAO AMAO B,对抑郁症和老年性痴呆具有潜在的作用。Rosiridin 在 10 μM 时对 MAO B 的抑制率为 83.8% (pIC50=5.38)。

Rosiridin(Synonyms: 络塞定)

Rosiridin Chemical Structure

CAS No. : 100462-37-1

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生物活性

Rosiridin inhibits MAO A and MAO B with potential beneficial effect in depression and senile dementia. Rosiridin shows an inhibition of 83.8% against MAO B at 10 μM (pIC50=5.38)[1].

IC50 & Target

pIC50: 5.38 (MAO B)[1]

体外研究
(In Vitro)

Rosiridin presents an inhibition 16.2±2.3 and 83.8±1.1% on MAO A and MAO B at a concentration of 10 μM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

332.39

Formula

C16H28O7

CAS 号

100462-37-1

中文名称

络塞定

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. van Diermen D, et al. Monoamine oxidase inhibition by Rhodiola rosea L. roots. J Ethnopharmacol. 2009 Mar 18;122(2):397-401.