Nimbin(Synonyms: 宁宾)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Nimbin (Synonyms: 宁宾)

Nimbin 是一种从 Azadirachta 中分离的中间体柠檬苦素,可防止 tau 聚集并增加细胞活力。Nimbin 有效抑制登革病毒 (dengue virus) 的包膜蛋白。Nimbin 具有抗炎,解热,抗真菌,抗组胺,防腐,抗氧化剂,抗癌和抗病毒特性,并可以穿越血脑屏障。

Nimbin(Synonyms: 宁宾)

Nimbin Chemical Structure

CAS No. : 5945-86-8

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生物活性

Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier[1][2][3].

分子量

540.60

Formula

C30H36O9

CAS 号

5945-86-8

中文名称

宁宾

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalini V Gorantla, et al. Neem Derivatives Inhibits Tau Aggregation. J Alzheimers Dis Rep. 2019 Jun 14;3(1):169-178.

    [2]. P Lavanya, et al. Computational Analysis Reveal Inhibitory Action of Nimbin Against Dengue Viral Envelope Protein. Virusdisease. 2015 Dec;26(4):243-54.

    [3]. Li-Juan Yang, et al. Host-guest System of Nimbin and Beta-Cyclodextrin or Its Derivatives: Preparation, Characterization, Inclusion Mode, and Solubilization. J Agric Food Chem. 2010 Aug 11;58(15):8545-52.