上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Furanodiene (Synonyms: 莪术呋喃二烯)
Furanodiene 是从姜黄中提取的天然萜类化合物。Furanodiene 通过抗血管生成和诱导 ROS 产生,DNA 链断裂和细胞凋亡发挥抗癌作用。Furanodiene 抑制外排转运蛋白 Pgp (P-glycoprotein) 功能并降低 Pgp 蛋白水平。
Furanodiene Chemical Structure
CAS No. : 19912-61-9
规格 | 是否有货 | ||
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5 mg | 询价 | ||
10 mg | 询价 | ||
25 mg | 询价 |
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生物活性 |
Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level[1]. |
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体外研究 (In Vitro) |
Furanodiene (1.4, 4.1, 12.2 uM; 48 hours) is effective in treating human JF 305 pancreatic cancer cells and MCF-7 breast cancer cells xenotranplanted into the zebrafish[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
216.32 |
Formula |
C15H20O |
CAS 号 |
19912-61-9 |
中文名称 |
莪术呋喃二烯 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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