Notoginsenoside Fc(Synonyms: 三七皂苷 FC)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Notoginsenoside Fc (Synonyms: 三七皂苷 FC)

Notoginsenoside Fc 是从三七叶中分离得到的一种原卟啉二醇 (PPD-) 型皂苷,可有效抵消血小板聚集。Notoginsenoside Fc 可以通过促进自噬促进糖尿病大鼠血管损伤后的内皮细胞再生。

Notoginsenoside Fc(Synonyms: 三七皂苷 FC)

Notoginsenoside Fc Chemical Structure

CAS No. : 88122-52-5

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生物活性

Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy[1].

体外研究
(In Vitro)

Notoginsenoside Fc (20 μM; for 24 h) markedly upregulates the expression of LC3B and Beclin 1 and downregulated that of p62 in RAOECs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Notoginsenoside Fc (3.5 mg/kg/day) accelerates reendothelialization and alleviates excessive neointimal formation following carotid artery injury in diabetic Sprague-Dawley rats (200±20 g) in vivo[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1211.38

Formula

C58H98O26

CAS 号

88122-52-5

中文名称

三七皂苷 FC

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Liu J, et al. Notoginsenoside Fc Accelerates Reendothelialization following Vascular Injury in Diabetic Rats by Promoting Endothelial Cell Autophagy. J Diabetes Res. 2019 Sep 3;2019:9696521.