上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Ilexhainanoside D (Synonyms: 海南冬青苷D)
Ilexhainanoside D 是从 Ilex hainanensis Merr. 中提取的主要三萜皂苷,Ilexhainanoside D 和 Ilexsaponin A1 联合使用后具有抗炎的作用。
Ilexhainanoside D Chemical Structure
CAS No. : 1137648-52-2
规格 | 是否有货 | ||
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5 mg | 询价 | ||
10 mg | 询价 | ||
25 mg | 询价 |
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生物活性 |
Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect[1]. |
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体内研究 (In Vivo) |
The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240 mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes/Bacteroidetes, reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
664.82 |
Formula |
C36H56O11 |
CAS 号 |
1137648-52-2 |
中文名称 |
海南冬青苷D |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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