天然产物 黄酮类 Flavonoids
Sulfuretin (Synonyms: 硫黄菊素)
Sulfuretin 通过抑制 NF-κB 通路来抑制炎症反应。 Sulfuretin 可用于过敏性气道炎症的研究。Sulfuretin 减少氧化应激、血小板聚集和诱变。Sulfuretin 是一种竞争性的有效单酚酶和二酚酶活性抑制剂，IC50 为 13.64 μM。
Sulfuretin Chemical Structure
CAS No. : 120-05-8
| 规格 | 是否有货 | ||
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| 5 mg | 询价 | ||
| 10 mg | 询价 | ||
| 25 mg | 询价 |
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| 生物活性 |
Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2]. |
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| 体外研究 (In Vitro) |
Sulfuretin is one of the main flavonoids produced by Rhus verniciflua. Sulfuretin efficiently inhibits the infiltration of inflammatory cells and attenuates allergic airway inflammation. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 体内研究 (In Vivo) |
Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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| 分子量 |
270.24 |
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| Formula |
C15H10O5 |
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| CAS 号 |
120-05-8 |
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| 中文名称 |
硫黄菊素 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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