3′,​4′,​5′,​5,​7-​Pentamethoxyflavone

天然产物 黄酮类 Flavonoids

3′,​4′,​5′,​5,​7-​Pentamethoxyflavone 

3′,4′,5′,5,7-Pentamethoxyflavone 是从 Rutaceae 中提取得到的一种天然黄铜类化合物,通过抑制Nrf2 通路克服化疗药物对癌细胞的导致的耐药性。

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3′,​4′,​5′,​5,​7-​Pentamethoxyflavone Chemical Structure

CAS No. : 53350-26-8

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生物活性

3′,4′,5′,5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway[1].

分子量

372.37

Formula

C20H20O7

CAS 号

53350-26-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hou X, et al. 3′,4′,5′,5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway. Mol Cells. 2015 May;38(5):396-401.