Kushenol B

天然产物 黄酮类 Flavonoids

Kushenol B 

Kushenol B 是一种从 S. flavescens 中分离得到的异戊二烯类黄酮,具有抗菌、抗炎和抗氧化活性。Kushenol B 对 cAMP 磷酸二酯酶 (cAMP PDE) 有抑制活性,IC50 为 31 µM。

Kushenol B

Kushenol B Chemical Structure

CAS No. : 99217-64-8

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生物活性

Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities[1]. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 µM[1].

IC50 & Target

IC50: 31 µM (cAMP PDE)[1]

分子量

492.60

Formula

C30H36O6

CAS 号

99217-64-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Han-Tian Fan, et al. The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore‑ and docking‑based virtual screening. Mol Med Rep