5,7,8-Trimethoxyflavone(Synonyms: Norwogonin 5,7,8-trimethyl ether)

天然产物 黄酮类 Flavonoids

5,7,8-Trimethoxyflavone (Synonyms: Norwogonin 5,7,8-trimethyl ether)

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) 来自于穿心莲,可以抑制 NOIC50 为 39.1 μM。5,7,8-Trimethoxyflavone 具有抗炎活性。

5,7,8-Trimethoxyflavone(Synonyms: Norwogonin 5,7,8-trimethyl ether)

5,7,8-Trimethoxyflavone Chemical Structure

CAS No. : 23050-38-6

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生物活性

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].

体外研究
(In Vitro)

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether; 8, 16, 32, 64 μM; for 24 hours) decreases NO production in a dose-dependent manner in RAW 264.7 macrophages. 5,7,8-Trimethoxyflavone does not change lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

312.32

Formula

C18H16O5

CAS 号

23050-38-6

中文名称

5,7,8-三甲氧基黄酮

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. De-Yang Shen, et al. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int J Mol Sci. 2012 Dec 27;14(1):496-514.