Kushenol X(Synonyms: 苦参醇X)

天然产物 黄酮类 Flavonoids

Kushenol X (Synonyms: 苦参醇X)

Kushenol X,一种从 Sophora flavescens 的根中分离出来的类黄酮化合物。Kushenol X 是一种有效的 β-葡萄糖醛酸苷酶 (β-glucuronidase) 和人羧酸酯酶 2 (hCE2) 抑制剂,IC50 分别为 2.07 μM 和 3.05 μM。

Kushenol X(Synonyms: 苦参醇X)

Kushenol X Chemical Structure

CAS No. : 254886-77-6

规格 是否有货
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生物活性

Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively[1][2].

IC50 & Target

IC50: 2.07 μM (β-glucuronidase)[1] and 3.05 μM (Human carboxylesterase 2 (hCE2))[2]

分子量

440.49

Formula

C25H28O7

CAS 号

254886-77-6

中文名称

苦参醇X

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Cheng-Peng Sun, et al. The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase. Int J Biol Macromol. 2020 Jan 15;143:349-358.

    [2]. Sha-Sha Song, et al. Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations. Int J Biol Macromol. 2019 Jun 15;131:201-208.