6-Methoxytricin(Synonyms: 6-甲氧基哌啶)

天然产物 黄酮类 Flavonoids

6-Methoxytricin (Synonyms: 6-甲氧基哌啶)

6-Methoxytricin (Compound 6) 6-甲氧基哌啶是从艾蒿 Artemisia iwayomogi 分离的类黄酮。6-Methoxytricin (Compound 6) 是醛糖还原酶 (AR) 和晚期糖基化终产物 (AGE) 的抑制剂,IC50 值分别为 30.29 μM 和 134.88 μM。6-Methoxytricin (Compound 6) 具有抗糖尿病并发症的潜力。

6-Methoxytricin(Synonyms: 6-甲氧基哌啶)

6-Methoxytricin Chemical Structure

CAS No. : 76015-42-4

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生物活性

6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC50 values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent[1].

IC50 & Target

IC50: 30.29 μM (AR); 134.88 μM (AGE) (6-​Methoxytricin)[1]

分子量

360.31

Formula

C18H16O8

CAS 号

76015-42-4

中文名称

6-甲氧基哌啶

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Lee YK, et al. Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds. Biomed Res Int. 2017;2017:7375615.