(±)-Taxifolin(Synonyms: (±)-二氢槲皮素; (±)-Dihydroquercetin)

发表于由

天然产物 黄酮类 Flavonoids

(±)-Taxifolin (Synonyms: (±)-二氢槲皮素; (±)-Dihydroquercetin)

(±)-Taxifolin ((±)-Dihydroquercetin) 是 Taxifolin 的消旋体。Taxifolin 具有重要的抗酪氨酸酶活性。Taxifolin 有效抑制胶原酶 (collagenase)，IC50 为 193.3 μM。Taxifolin是一种重要的天然化合物，具有抗纤维化作用。Taxifolin 是一种自由基清除剂具有抗氧化能力。

(±)-Taxifolin(Synonyms: (±)-二氢槲皮素; (±)-Dihydroquercetin)

(±)-Taxifolin Chemical Structure

CAS No. : 24198-97-8

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生物活性

(±)-Taxifolin ((±)-Dihydroquercetin) is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity[2].

分子量

304.25

Formula

C15H12O7
CAS 号

24198-97-8
中文名称

(±)-花旗松素；(±)-紫杉叶素；(±)-二氢槲皮素；(±)-黄杉素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Angelis A, et al. Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties. Molecules. 2016 Nov 21;21(11):1586.

    [2]. Lei Ren, et al. Dissecting Efficacy and Metabolic Characteristic Mechanism of Taxifolin on Renal Fibrosis by Multivariate Approach and Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometry-Based Metabolomics Strategy. Front Pharmacol. 2021 Jan 14;11:608511.