天然产物 黄酮类 Flavonoids
Apigenin-7-glucuronide (Synonyms: Apigenin 7-O-glucuronide) 纯度: 98.83%
Apigenin-7-glucuronide 能够抑制基质金属蛋白酶 (MMP) 的活性,其对 MMP-3,MMP-8,MMP-9,MMP-13 的IC50 值分别为 12.87,22.39,17.52,0.27 μM。
Apigenin-7-glucuronide Chemical Structure
CAS No. : 29741-09-1
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥1650 | In-stock | |
5 mg | ¥1500 | In-stock | |
10 mg | ¥2500 | In-stock | |
25 mg | ¥4500 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Apigenin-7-glucuronide 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Metabolism/Protease Compound Library
- Natural Product Library
- Anti-Cancer Compound Library
- Differentiation Inducing Compound Library
- Glycoside Compound Library
- Phenols Library
- Flavonoids Library
- Anti-Pancreatic Cancer Compound Library
- Angiogenesis Related Compound Library
- Food-Sourced Compound Library
生物活性 |
Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively. |
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IC50 & Target |
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体外研究 (In Vitro) |
Apigenin-7-Oglucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively [1]. Scutellarin A also inhibits the migrated capacity of ACHN and 786-O cells in a dose-dependent manner. It is also revealed that after treatment with Scutellarin A (30, 60, and 90 μM) for 24 h, the apoptosis rates in ACHN and 786-O cells are remarkably enhanced dose-dependently when compared to the control groups[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
446.36 |
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Formula |
C21H18O11 |
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CAS 号 |
29741-09-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (560.09 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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