天然产物 黄酮类 Flavonoids
3,5,6,7,8,3′,4′-Heptemthoxyflavone 纯度: 99.85%
3,5,6,7,8,3′,4′-Heptemthoxyflavone 是一种蜜柑皮中的黄酮,具有抗肿瘤起始活性和抗神经炎症活性。3,5,6,7,8,3′,4′-Heptemthoxyflavone 能抑制胶原酶的活性,增加人真皮成纤维细胞新生 (HDFn) 细胞中 I 型前胶原的含量。3,5,6,7,8,3′,4′-Heptemthoxyflavone 能通过 cAMP/ERK/CREB 信号诱导脑源性神经营养因子(BDNF) 表达,降低 C6 细胞磷酸二酯酶活性。
3,5,6,7,8,3′,4′-Heptemthoxyflavone Chemical Structure
CAS No. : 1178-24-1
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥3430 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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3,5,6,7,8,3′,4′-Heptemthoxyflavone 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Natural Product Library
- Anti-Cancer Compound Library
- Traditional Chinese Medicine Monomer Library
- Flavonoids Library
- Transcription Factor Targeted Library
- Food-Sourced Compound Library
生物活性 |
3,5,6,7,8,3′,4′-heptamethoxyflavone, a flavonoid in C. unshiu peels, exhibits anti-tumor-initiating effect and Anti-neuroinflammatory activity[1][2][3]. 3,5,6,7,8,3′,4′-heptamethoxyflavone inhibits collagenase activity and increased type I procollagen content in HDFn cells[1]. 3,5,6,7,8,3′,4′-heptamethoxyflavone induces brain-derived neurotrophic factor (BDNF) expression via cAMP/ERK/CREB signaling and reduces phosphodiesterase activity in C6 cells[4]. |
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分子量 |
432.42 |
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Formula |
C22H24O9 |
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CAS 号 |
1178-24-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (115.63 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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