(E)-Flavokawain A(Synonyms: 卡瓦胡椒素A)

发表于由

天然产物 黄酮类 Flavonoids

(E)-Flavokawain A (Synonyms: 卡瓦胡椒素A) 纯度: 99.29%

(E)-Flavokawain A 是从卡瓦胡椒中提取的查尔酮，具有抗癌作用。(E)-Flavokawain A 通过介入 bax 蛋白依赖和线粒体依赖的凋亡通路，诱导膀胱癌细胞凋亡，抑制小鼠肿瘤生长。

(E)-Flavokawain A(Synonyms: 卡瓦胡椒素A)

(E)-Flavokawain A Chemical Structure

CAS No. : 37951-13-6

规格 价格 是否有货 数量
5 mg ￥500 In-stock
10 mg ￥900 In-stock
20 mg ￥1500 In-stock
50 mg   询价  
100 mg   询价  

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(E)-Flavokawain A 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Apoptosis Compound Library
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Phenols Library
  • Flavonoids Library

生物活性

(E)-Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. (E)-Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].

分子量

314.33

Formula

C18H18O5
CAS 号

37951-13-6
中文名称

卡瓦胡椒素A
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

DMSO : 25 mg/mL (79.53 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.1814 mL 15.9069 mL 31.8137 mL
5 mM 0.6363 mL 3.1814 mL 6.3627 mL
10 mM 0.3181 mL 1.5907 mL 3.1814 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Zi X, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.