天然产物 黄酮类 Flavonoids
7,3′,4′-Tri-O-methylluteolin (Synonyms: 木犀草素-7,3′,4′-三甲醚; 5-Hydroxy-3′,4′,7-trimethoxyflavone) 纯度: 99.28%
7,3′,4′-Tri-O-methylluteolin (5-Hydroxy-3′,4′,7-trimethoxyflavone) 是一种类黄酮化合物,通过抑制炎症介质、NO、PGE2 和促炎细胞因子的释放,在 LPS 诱导的巨噬细胞系中具有强大的抗炎作用。7,3′,4′-Tri-O-methylluteolin 显著降低诱导型一氧化氮合酶和环加氧酶-2 的 mRNA 表达。
7,3′,4′-Tri-O-methylluteolin Chemical Structure
CAS No. : 29080-58-8
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥970 | In-stock | |
5 mg | ¥1900 | In-stock | |
10 mg | ¥2900 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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7,3′,4′-Tri-O-methylluteolin 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Apoptosis Compound Library
- Immunology/Inflammation Compound Library
- Natural Product Library
- Anti-Aging Compound Library
- Differentiation Inducing Compound Library
- Phenols Library
- Pyroptosis Compound Library
- Traditional Chinese Medicine Monomer Library
- Flavonoids Library
- Anti-Pancreatic Cancer Compound Library
- Angiogenesis Related Compound Library
- Anti-Colorectal Cancer Compound Library
生物活性 |
7,3′,4′-Tri-O-methylluteolin (5-Hydroxy-3′,4′,7-trimethoxyflavone), a flavonoid compound, possesses potent anti-inflammatory effects in LPS-induced macrophage cell line mediated by inhibition of release of inflammatory mediators, NO, PGE2, and pro-inflammatory cytokines. 7,3′,4′-Tri-O-methylluteolin significantly induces reduction in the mRNA expressions of inducible nitric oxide synthase and cyclooxygenase-2[1]. |
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IC50 & Target[1] |
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分子量 |
328.32 |
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Formula |
C18H16O6 |
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CAS 号 |
29080-58-8 |
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中文名称 |
木犀草素-7,3′,4′-三甲醚;3’4’7-三甲氧基-5-羟基黄酮 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 20 mg/mL (60.92 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
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参考文献 |
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