天然产物 黄酮类 Flavonoids
Semilicoisoflavone B (Synonyms: 半甘草异黄酮 B)
Semilicoisoflavone B，一种异黄酮，主要来源于 Glycyrrhiza uralensis Fisch.。Semilicoisoflavone B 通过抑制 β-分泌酶-1 (BACE1) 的表达和活性来减少淀粉样蛋白 β (amyloid β，Aβ) 的分泌。Semilicoisoflavone B 主要通过增加 PPARγ 表达和抑制 STAT3 磷酸化来降低 BACE1 的表达。
Semilicoisoflavone B Chemical Structure
CAS No. : 129280-33-7
| 规格 | 是否有货 | ||
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| 5 mg | 询价 | ||
| 10 mg | 询价 | ||
| 25 mg | 询价 |
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| 生物活性 |
Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1]. |
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| 分子量 |
352.34 |
| Formula |
C20H16O6 |
| CAS 号 |
129280-33-7 |
| 中文名称 |
半甘草异黄酮 B |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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