Onjisaponin B(Synonyms: 远志皂苷B)

天然产物 糖类和糖苷 Saccharides and Glycosides

Onjisaponin B;(Synonyms: 远志皂苷B) 纯度: 99.10%

Onjisaponin B 是一种从远志中提取的天然产物。在 PC-12 细胞中,Onjisaponin B 能促进自噬,加速突变 α- 突触核蛋白和亨廷顿蛋白的降解,可用于帕金森病和亨廷顿病的研究。

Onjisaponin B(Synonyms: 远志皂苷B)

Onjisaponin B Chemical Structure

CAS No. : 35906-36-6

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5 mg ¥2690 In-stock
10 mg ¥4570 In-stock
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Onjisaponin B 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

生物活性

Onjisaponin B is a natural product derived from Radix Polygalae. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells, and exbibits potential therapeutic effects on Parkinson disease and Huntington disease[1].

分子量

1573.67

Formula

C75H112O35

CAS 号

35906-36-6

中文名称

远志皂苷B

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Wu AG, et al. Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells. Int J Mol Sci. 2013 Nov 15;14(11):22618-41.