天然产物 糖类和糖苷 Saccharides and Glycosides
Anemarsaponin B;(Synonyms: 知母皂苷 B)
Anemarsaponin B 是一种甾体皂苷。Anemarsaponin B 降低 iNOS 和 COX-2 的蛋白和 mRNA 水平。Anemarsaponin B 减少促炎细胞因子的表达和产生，包括 TNF-α 和 IL-6。Anemarsaponin B 通过阻断 IκBα 的磷酸化来抑制 NF-κB 的 p65 亚基的核转位。Anemarsaponin B 还抑制 MAP 激酶激酶 3/6 (MKK3/6) 和混合谱系激酶 3 (MLK3) 的磷酸化。 具有抗炎作用。
Anemarsaponin B Chemical Structure
CAS No. : 139051-27-7
| 规格 | 价格 | 是否有货 | |
|---|---|---|---|
| 5 mg | ￥2690 | 询问价格 货期 | |
| 10 mg | ￥4570 | 询问价格 货期 | |
* Please select Quantity before adding items.
| 生物活性 |
Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect [1]. |
|||
|---|---|---|---|---|
| IC50 Target[1] |
|
|||
| 分子量 |
903.06 |
|||
| Formula |
C45H74O18 |
|||
| CAS 号 |
139051-27-7 |
|||
| 中文名称 |
知母皂苷 B |
|||
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
|||
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
|||
| 参考文献 |
|