Xanthohumol D

天然产物 糖类和糖苷 Saccharides and Glycosides

Xanthohumol D; 纯度: 99.21%

Xanthohumol D,分离于酒花,是一种醌还原酶2 (QR-2) 抑制剂,IC50 为110 μM,并与 QR-2 活性位点结合。Xanthohumol D 在体外对人癌细胞株有抗增殖作用。

Xanthohumol D

Xanthohumol D Chemical Structure

CAS No. : 274675-25-1

规格 价格 是否有货 数量
1 mg ¥3000 In-stock
5 mg ¥8600 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro[1][2].

IC50 Target

IC50: 110 μM (Quinone reductase-2)[1]

分子量

370.40

Formula

C21H22O6

CAS 号

274675-25-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

参考文献
  • [1]. Choi Y, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Anal Chem. 2011 Feb 1;83(3):1048-52.

    [2]. Tronina T, et al. Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro. Bioorg Med Chem. 2013 Apr 1;21(7):2001-6.