天然产物 糖类和糖苷 Saccharides and Glycosides
Escin IIa;
Escin IIa 是从七叶树种子七叶树中分离出来的，对动物急性炎症有积极作用。Escin IIa 对乙醇诱导的胃粘膜损伤有明显的保护作用。
Escin IIa Chemical Structure
CAS No. : 158732-55-9
| 规格 | 是否有货 | ||
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| 5 mg | 询价 | ||
| 10 mg | 询价 | ||
| 25 mg | 询价 |
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| 生物活性 |
Escin IIa, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIa has gastroprotections on ethanol-induced gastric mucosal lesions in rats[1][2]. |
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| 体内研究 (In Vivo) |
Escins Ia, Ib, IIa, and IIb (50-200 mg/kg) inhibits the increase of vascular permeability induced by both acetic acid in mice and histamine in rats. Escins Ib, IIa, and IIb (50-200 mg/kg) also inhibit that induced by serotonin in rats, but escin Ia didn’t. Escins Ia, Ib, IIa, and IIb (200 mg/kg) inhibit the hind paw edema induced by carrageenin at the first phase in rats. Escin Ia (200 mg/kg) and escins Ib, IIa, and IIb (50-200 mg/kg) inhibit the scratching behavior induced by compound 48/80 in mice, but escin Ia was weakest[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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| 分子量 |
1101.23 |
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| Formula |
C54H84O23 |
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| CAS 号 |
158732-55-9 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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