Aloe-emodin-8-O-β-D-glucopyranoside(Synonyms: 芦荟大黄素-8-O-β-D-葡萄糖苷)

天然产物 糖类和糖苷 Saccharides and Glycosides

Aloe-emodin-8-O-β-D-glucopyranoside;(Synonyms: 芦荟大黄素-8-O-β-D-葡萄糖苷)

Aloe-emodin-8-O-β-D-glucopyranoside 是从 Saussrurea lappa 中分离出的化合物,是温和的人类蛋白酪氨酸磷酸酶 1B (hPTP1B) 抑制剂,其 IC50 值为 26.6 μM。

Aloe-emodin-8-O-β-D-glucopyranoside(Synonyms: 芦荟大黄素-8-O-β-D-葡萄糖苷)

Aloe-emodin-8-O-β-D-glucopyranoside Chemical Structure

CAS No. : 33037-46-6

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生物活性

Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC50 of 26.6 μM[1].

IC50 Target

IC50:26.6 μM (hPTP1B)[1]

分子量

432.38

Formula

C21H20O10

CAS 号

33037-46-6

中文名称

芦荟大黄素-8-O-β-D-葡萄糖苷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Li S, et al. PTP1B inhibitors from Saussrurea lappa. J Asian Nat Prod Res. 2006 Apr-May;8(3):281-6.