Buddlejasaponin IV

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Buddlejasaponin IV;

Buddlejasaponin IV (BS-IV) 对癌细胞具有抗炎和细胞毒性作用。

Buddlejasaponin IV

Buddlejasaponin IV Chemical Structure

CAS No. : 139523-30-1

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生物活性

Buddlejasaponin IV (BS‐IV) exerts anti-inflammatory and cytotoxic effects against cancer cells[1].

体外研究
(In Vitro)

Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes[1].
Buddlejasaponin IV (BS-IV) exhibits anti-inflammatory effect of through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-κB inactivation[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

943.12

Formula

C48H78O18
CAS 号

139523-30-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Young Sun Hwang, et al. Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes. Phytother Res. 2011 Oct;25(10):1503-10.

    [2]. Jong-Heon Won, et al. Anti-inflammatory effect of buddlejasaponin IV through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-kappaB inactivation. Br J Pharmacol. 2006 May;148(2):216-25.