Bruceine E(Synonyms: 鸦胆子素E)

天然产物 糖类和糖苷 Saccharides and Glycosides

Bruceine E;(Synonyms: 鸦胆子素E)

Bruceine E 是鸦胆子种子中的类青霉素,具有降血糖作用。Bruceine E 对非糖尿病小鼠和链脲霉素 (STZ) 诱导的糖尿病大鼠均有降血糖作用。

Bruceine E(Synonyms: 鸦胆子素E)

Bruceine E Chemical Structure

CAS No. : 21586-90-3

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ)-induced diabetic rats at lower dose[2].

体内研究
(In Vivo)

Bruceine D and E, isolated from B. javanica seeds, exhibits blood glucose lowering effect in both nondiabetic mice and STZ-induced diabetic rats at lower dose (1 mg/kg b.w.) during 0-8 h screening[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

412.43

Formula

C20H28O9

CAS 号

21586-90-3

中文名称

鸦胆子素E

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188.

    [2]. Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17(1):94. Published 2017 Feb 6.