天然产物 糖类和糖苷 Saccharides and Glycosides
Niga-ichigoside F1;(Synonyms: 苦莓苷F1)
Niga-ichigoside F1 是一种具有口服活性熊果三萜，具有抗高血脂和抗氧化活性。Niga-ichigoside F1 可以预防高脂肪饮食 (HFD) 诱导的肝脂肪变性。
Niga-ichigoside F1 Chemical Structure
CAS No. : 95262-48-9
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 5 mg | ￥5200 | In-stock | |
| 10 mg | ￥8400 | In-stock | |
| 50 mg | ; | 询价 | ; |
| 100 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
Niga-ichigoside F1 相关产品
bull;相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Natural Product Library
- Glycoside Compound Library
- Anti-Cardiovascular Disease Compound Library
- Terpenoids Library
- Orally Active Compound Library
- Traditional Chinese Medicine Monomer Library
| 生物活性 |
Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis[1]. |
|---|---|
| 体外研究 (In Vitro) |
Niga-ichigoside F1 (2.5, 5, 10, 20 μM; for 24 hours) inhibits lipid accumu-lation in free fatty acid (FFA)-treated HepG2 cells in a dose-dependent manner. Niga-ichigoside F1 has no effects on cell viability[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 (In Vivo) |
Niga-ichigoside F1 (40 mg/kg; oral gavage; for 12 weeks) alleviates hepatic steatosis, possibly by significantly interacting with high-fat diet (HFD) to regulate lipid metabolism genes (including Srebp1c, Acc1, Fasn, Scd1, Cpt1a and Fabp5) in four-week-old male C57BL/6J mice[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
666.84 |
| Formula |
C36H58O11 |
| CAS 号 |
95262-48-9 |
| 中文名称 |
苦莓苷F1 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
4deg;C, protect from light *In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light) |
| 参考文献 |
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