Chrysophanol triglucoside(Synonyms: 大黄酚-1-O-Β-三葡萄糖苷)

天然产物 糖类和糖苷 Saccharides and Glycosides

Chrysophanol triglucoside;(Synonyms: 大黄酚-1-O-Β-三葡萄糖苷)

Chrysophanol triglucoside 是一种从决明子中分离出的蒽醌类化合物,可抑制蛋白酪氨酸磷酸酶 1B (PTP1B)α-glucosidaseIC50 值分别为80.17 和 197.06 µM。Chrysophanol triglucoside 具有糖尿病研究的潜力。

Chrysophanol triglucoside(Synonyms: 大黄酚-1-O-Β-三葡萄糖苷)

Chrysophanol triglucoside Chemical Structure

CAS No. : 120181-07-9

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生物活性

Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase with IC50s of 80.17 and 197.06 µM, respectively. Chrysophanol triglucoside has the potential for diabetes research[1].

IC50 Target

IC50: 80.17 µM (PTP1B), 197.06 µM (α-glucosidase)[1]

分子量

740.66

Formula

C33H40O19

CAS 号

120181-07-9

中文名称

大黄酚-1-O-Β-三葡萄糖苷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jung HA, et, al. Promising Inhibitory Effects of Anthraquinones, Naphthopyrone, and Naphthalene Glycosides, from Cassia obtusifolia on α-Glucosidase and Human Protein Tyrosine Phosphatases 1B. Molecules. 2016 Dec 27; 22(1): 28.