Cytidine 5′-diphosphate trisodium salt(Synonyms: CDP)

天然产物 糖类和糖苷 Saccharides and Glycosides

Cytidine 5′-diphosphate trisodium salt;(Synonyms: CDP) 纯度: ge;98.0%

Cytidine 5′-diphosphate trisodium salt (CDP) 是由尿苷单磷酸激酶 (UMPK) 催化的磷酸基团从 ATP 转移到胞苷单磷酸 (CMP) 产生的。Cytidine 5′-diphosphate trisodium salt 可用于生产胞苷三磷酸 (CTP) 以合成 DNA 和 RNA。

Cytidine 5

Cytidine 5′-diphosphate trisodium salt Chemical Structure

CAS No. : 34393-59-4

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Cytidine 5′-diphosphate trisodium salt 相关产品

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生物活性

Cytidine 5′-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

体内研究
(In Vivo)

CDP-ribitol can be used for the Diagnostics and research of CDP-l-ribitol pyrophosphorylase A (CRPPA) muscular dystrophy[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

469.12

Formula

C9H12N3Na3O11P2

CAS 号

34393-59-4

中文名称

胞苷-5′-二磷酸三钠盐;胞苷5′-二磷酸三钠盐水合物;胞苷-5-二磷酸三钠盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20deg;C, protect from light, stored under nitrogen

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro:;

H2O : 250 mg/mL (532.91 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1317 mL 10.6583 mL 21.3165 mL
5 mM 0.4263 mL 2.1317 mL 4.2633 mL
10 mM 0.2132 mL 1.0658 mL 2.1317 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Moffatt BA, et, al. Purine and pyrimidine nucleotide synthesis and metabolism. Arabidopsis Book. 2002;1:e0018.

    [2]. Salvador-Silva M, et, al. Microglial cells in the retina of Carassius auratus: effects of optic nerve crush. J Comp Neurol. 2000 Feb 21;417(4):431-47.

    [3]. Tol W, et, al. Cytidine Diphosphate-Ribitol Analysis for Diagnostics and Treatment Monitoring of Cytidine Diphosphate-l-Ribitol Pyrophosphorylase A Muscular Dystrophy. Clin Chem. 2019 Oct;65(10):1295-1306.