Deoxycytidine triphosphate(Synonyms: dCTP; 2′-Deoxycytidine-5′-triphosphate)

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生化分析试剂 Biochemical Assay Reagents
Deoxycytidine triphosphate;(Synonyms: dCTP; 2′-Deoxycytidine-5′-triphosphate)

Deoxycytidine triphosphate (dCTP) 是可用于 DNA 合成 (DNA synthesis) 的核苷三磷酸。Deoxycytidine triphosphate 可用于实时 PCR，cDNA 合成 和 DNA 测序等研究。

Deoxycytidine triphosphate(Synonyms: dCTP; 2′-Deoxycytidine-5′-triphosphate)

Deoxycytidine triphosphate Chemical Structure

CAS No. : 2056-98-6

规格 价格 是否有货 数量
10;mM;*;1 mL in Water ￥880 In-stock
10 mg ￥800 In-stock
50 mg ￥1800 询价
100 mg ; 询价 ;
200 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing[1][2][3].

IC50 Target

Human Endogenous Metabolite

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体外研究
(In Vitro)

Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C[1].
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

467.16

Formula

C9H16N3O13P3
CAS 号

2056-98-6
中文名称

脱氧胞苷三磷酸；三磷酸脱氧胞苷；2′-脱氧胞苷-5′-三磷酸
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 50 mg/mL (107.03 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1406 mL 10.7030 mL 21.4059 mL
5 mM 0.4281 mL 2.1406 mL 4.2812 mL
10 mM 0.2141 mL 1.0703 mL 2.1406 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. A W Harris, et al. Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1979 Feb;39(2 Pt 1):538-41.

    [2]. B A Bladergroen, et al. CTP:phosphoethanolamine cytidylyltransferase. Biochim Biophys Acta. 1997 Sep 4;1348(1-2):91-9.

    [3]. M H Tattersall, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975 Apr;5(2):191-202.