Msr-Ratio(Synonyms: Msr-green)

发表于由

Msr-Ratio;(Synonyms: Msr-green)

Msr-Ratio (Msr-green)是一种比率型甲硫氨酸亚砜还原酶 (methionine sulfoxide reductase) 的荧光探针 (λex=375 nm, λem=550 nm)。Msr-Ratio 可用于监测体外和活细胞中的甲硫氨酸亚砜还原酶活性。

Msr-Ratioamp;;(Synonyms: Msr-green)

Msr-Ratio Chemical Structure

CAS No. : 2290635-22-0

规格 价格 是否有货
5 mg ￥3000 询问价格 货期
10 mg ￥4800 询问价格 货期

* Please select Quantity before adding items.

生物活性

Msr-Ratio (Msr-green) is a ratiometric fluorescent probe of methionine sulfoxide reductase (λex=375 nm, λem=550 nm). Msr-Ratio is used for monitoring the enzyme activity in vitro and in live cells[1].

体外研究
(In Vitro)

Msr-Ratio is converted to its corresponding sulfide form by methionine sulfoxide reductase. Msr-Ratio displays favorable properties such as a nearly 400-fold fluorescence change, fast response rate (<30 min), large stokes shift (120 nm), and green emission (550 nm)[1].
There is a very weak background signal in live HL60 cells after the addition of Msr-Ratio. As the Msr-Ratio (10 μM) incubation time increased in cells from 0 to 8 h, the fluorescence signal constantly strengthened[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

310.37

Formula

C18H14O3S
CAS 号

2290635-22-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Liangwei Zhang, et al. A ratiometric fluorescent probe of methionine sulfoxide reductase with an improved response rate and emission wavelength. Chem Commun (Camb). 2019 Jan 29;55(10):1502-1505.