HKSOX-1m (5/6-mixture) (hydrobromide)

HKSOX-1m (5/6-mixture) (hydrobromide);

HKSOX-1m (5/6-mixture) hydrobromide 是靶向线粒体的 O2•− 荧光探针,具有极好的选择性,且在较大范围的 pH 值区间,细胞中即使有大量强氧化剂和还原剂的时候依然有效。

HKSOX-1m (5/6-mixture) (hydrobromide)amp;;

HKSOX-1m (5/6-mixture) (hydrobromide) Chemical Structure

规格 价格 是否有货
1 mg ¥3000 询问价格 货期

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生物活性

HKSOX-1m (5/6-mixture) hydrobromide is a O2•− fluorescent probe for mitochondria-targeting, exhibiting excellent selectivity and sensitivity toward O2•− over a broad range of pH, strong oxidants, and abundant reductants found in cells[1].

体外研究
(In Vitro)

HKSOX-1m (5/6-mixture) hydrobromide (10 μM) sensitively captures signals for basal and Antimycin A (1 μM)-stimulated mitochondrial O2•− in differentiated human THP-1 cells, at very low laser power output (1% intensity at Ex 514 nm on Zeiss LSM 510 Meta)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1258.72

Formula

C98H74Br4F20N4O20P2S4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

参考文献
  • [1]. Jun Jacob Hu, et al. Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo. J Am Chem Soc . 2015 Jun 3;137(21):6837-43.