L-Alanyl-L-glutamine(Synonyms: L-丙氨酸-L-谷氨酰胺)

发表于由

L-Alanyl-L-glutamine;(Synonyms: L-丙氨酸-L-谷氨酰胺) 纯度: ge;97.0%

L-Alanyl-L-glutamine 是一种谷氨酰胺二肽，对抗氧化系统有益，可减轻炎症，并可能在分解代谢情况下调节热休克蛋白 (HSP) 的反应。

L-Alanyl-L-glutamineamp;;(Synonyms: L-丙氨酸-L-谷氨酰胺)

L-Alanyl-L-glutamine Chemical Structure

CAS No. : 39537-23-0

规格 价格 是否有货 数量
10;mM;*;1 mL in Water ￥610 In-stock
100 mg ￥550 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

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L-Alanyl-L-glutamine 相关产品

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  • Immunology/Inflammation Compound Library
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  • Human Endogenous Metabolite Compound Library
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生物活性

L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations[1].

IC50 Target

Human Endogenous Metabolite

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体外研究
(In Vitro)

L-Alanyl-L-glutamine (2 mM; 24 hours) partially or fully attenuates chronic insulin secretion, and IR-β and COX IV levels which are decreased when β-cells were exposed to macrophages following stimulation in vitro (IMMs)[1].
L-Alanyl-L-glutamine -dependent β-cell protection mediated by coordinated effects on the glutamine-GSH axis, and the HSP pathway, maintenance of mitochondrial metabolism and stimulus-secretion coupling essential for insulin release[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

217.22

Formula

C8H15N3O4
CAS 号

39537-23-0
中文名称

L-丙氨酸-L-谷氨酰胺；丙氨酰谷氨酰胺；丙谷二肽；力肽
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 100 mg/mL (460.36 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.6036 mL 23.0181 mL 46.0363 mL
5 mM 0.9207 mL 4.6036 mL 9.2073 mL
10 mM 0.4604 mL 2.3018 mL 4.6036 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Cruzat VF,et al. Alanyl-glutamine improves pancreatic β-cell function following ex vivo inflammatory challenge. J Endocrinol. 2015 Mar;224(3):261-71.