GPLGIAGQ TFA; 纯度: 99.67%
GPLGIAGQ TFA 是一种 MMP2 可降解 (cleavable) 的多肽,在脂质体和胶束纳米载体中都被用作刺激敏感的连接物,用于 MMP2 触发的肿瘤靶向研究。GPLGIAGQ可用于合成光动力疗法 (PDT) 中独特的MMP2靶向光敏剂。
GPLGIAGQ TFA Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
10;mM;*;1 mL in DMSO | ¥1360 | In-stock | |
5 mg | ¥1000 | In-stock | |
10 mg | ¥1500 | In-stock | |
50 mg | ¥3500 | In-stock | |
100 mg | ; | 询价 | ; |
200 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
GPLGIAGQ TFA 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Apoptosis Compound Library
- Metabolism/Protease Compound Library
- Anti-Cancer Compound Library
- Anti-Pancreatic Cancer Compound Library
- Angiogenesis Related Compound Library
- Peptide Library
生物活性 |
GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT)[1][2][3]. |
IC50 Target |
MMP2[1]. |
||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
体外研究 (In Vitro) |
GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||
分子量 |
825.83 |
||||||||||||||||
Formula |
C33H54F3N9O12 |
||||||||||||||||
Sequence |
Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln |
||||||||||||||||
Sequence Shortening |
GPLGIAGQ |
||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||
储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
||||||||||||||||
溶解性数据 |
In Vitro:;
DMSO : 50 mg/mL (60.55 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
|
||||||||||||||||
参考文献 |
|