Fibrinopeptide B, human TFA(Synonyms: FPB,human TFA)

Fibrinopeptide B, human TFA;(Synonyms: FPB,human TFA) 纯度: 99.81%

Fibrinopeptide B, human TFA (FPB,human TFA) 是由 14 个氨基酸组成的多肽,从纤维蛋白原β链氨基末端释放出来。

Fibrinopeptide B, human TFAamp;;(Synonyms: FPB,human TFA)

Fibrinopeptide B, human TFA Chemical Structure

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1 mg ¥900 In-stock
5 mg ¥3600 In-stock
10 mg ¥6200 In-stock
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Fibrinopeptide B, human TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Fibrinopeptide B, human TFA (FPB,human TFA), human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin[1].

体外研究
(In Vitro)

Fibrinopeptide B, human is released from the amino-terminus of the B 3-chains of fibrinogen by thrombin. Fibrinopeptide B, human (hFpB, 10 nM) causes directed cell migration of neutrophils (PMN), and fibroblasts. Fibrinopeptide B, human also possesses potent chemotactic activity relative to human complement (C5a), leukotriene B4 (LTB4), and formyl-methionylleucyl-phenylalanine (fMLP), and for fibroblasts its chemotactic activity is comparable to that of platelet-derived growth factor. However, Fibrinopeptide B, human is not chemotactic for monocytes, and shows no interaction with PMN receptor for C5a, LTB4, or fMLP[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1666.58

Formula

C68H94F3N19O27

Sequence

{Glp}-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg

Sequence Shortening

{Glp}-GVNDNEEGFSAR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

H2O : 1.25 mg/mL (0.75 mM; Need ultrasonic)

参考文献
  • [1]. Senior RM, et al. Effects of fibrinogen derivatives upon the inflammatory response. Studies with human fibrinopeptide B. J Clin Invest. 1986 Mar;77(3):1014-9.