EPQpYEEIPIYL; 纯度: 98.56%
EPQpYEEIPIYL 是一种磷酸肽,是 Src 同源 2 (SH2) 结构域配体。 EPQpYEEIPIYL 通过与 SH2 域结合来激活 Src 家族成员 (例如 Lck,Hck,Fyn)。
EPQpYEEIPIYL Chemical Structure
CAS No. : 147612-86-0
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥4000 | In-stock | |
5 mg | ¥14000 | In-stock | |
10 mg | ; | 询价 | ; |
50 mg | ; | 询价 | ; |
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EPQpYEEIPIYL 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Peptide Library
生物活性 |
EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains[1][2]. |
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体外研究 (In Vitro) |
The hmT-derived phosphopeptide, pY324, which has the sequence EPQpYEEIPIYL, shows the highest affinity binding to GST fusion proteins of the Lck SH2 domain (5-fold higher than Lck’s affinity-for the Lck tail phosphopeptide) and the Src SH2 domain (44-fold higher than Src’s affinity for the Src tail phosphopeptide)[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
1473.52 |
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Formula |
C66H97N12O24P |
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CAS 号 |
147612-86-0 |
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Sequence Shortening |
EPQpYEEIPIYL |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:;
H2O : 2 mg/mL (1.36 mM; ultrasonic and adjust pH to 2 with HCl) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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