CCP peptide;
CCP peptide 是一种合成的环状瓜氨酸化肽 (CCP),用作血清学检测抗 CCP 抗体的底物。CCP peptide 可作为自身抗体的靶标,对类风湿关节炎 (RA) 具有很高的特异性。
CCP peptide Chemical Structure
CAS No. : 277748-59-1
规格 | 是否有货 | ||
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100 mg | ; | 询价 | ; |
250 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
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CCP peptide 的其他形式现货产品:
生物活性 |
CCP peptide is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA)[1][2]. |
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体内研究 (In Vivo) |
CCP peptide is used as a new antigenic substrate in anti-CCP ELISA to detect anti-citrullinated protein antibodies (ACPAs). The anti-CCP ELISA is extremely specific (98%), with a reasonable sensitivity (68%). The anti-CCP ELISA is very useful for diagnostic and therapeutic strategies in rheumatoid arthritis (RA)[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
2341.47 |
Formula |
C87H145N41O32S2 |
CAS 号 |
277748-59-1 |
Sequence |
His-Gln-Cys-His-Gln-Glu-Ser-Thr-{Cit}-Gly-Arg-Ser-Arg-Gly-Arg-Cys-Gly-Arg-Ser-Gly-Ser (Disulfide bridge: Cys3-Cys16) |
Sequence Shortening |
HQCHQEST-{Cit}-GRSRGRCGRSGS (Disulfide bridge: Cys3-Cys16) |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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