N-CBZ-Phe-Arg-AMC(Synonyms: Z-FR-AMC)

N-CBZ-Phe-Arg-AMC;(Synonyms: Z-FR-AMC)

N-CBZ-Phe-Arg-AMC (Z-FR-AMC) 是一种组织蛋白酶底物,可用于评估溶酶体组织蛋白酶的活性。

N-CBZ-Phe-Arg-AMCamp;;(Synonyms: Z-FR-AMC)

N-CBZ-Phe-Arg-AMC Chemical Structure

CAS No. : 65147-22-0

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].

分子量

612.68

Formula

C33H36N6O6

CAS 号

65147-22-0

Sequence

CBZ-Phe-Arg-AMC

Sequence Shortening

CBZ-FR-AMC

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Xu P, et al. Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):246-53.

    [2]. Porter K,et al. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy. 2013 Apr;9(4):581-94.