AUNP-12;(Synonyms: NP-12)
AUNP-12 (NP-12) 是 PD-1 信号通路的一种多肽拮抗剂,在抑制淋巴细胞增殖和效应功能方面对 PD-L1 和 PD-L2 具有等效的拮抗作用。AUNP-12 具有免疫激活作用、良好的抗肿瘤活性,具有更好的研究免疫相关不良事件 (irAEs) 的潜力。
AUNP-12 Chemical Structure
CAS No. : 1353563-85-5
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100 mg | ; | 询价 | ; |
250 mg | ; | 询价 | ; |
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AUNP-12 的其他形式现货产品:
生物活性 |
AUNP-12 (NP-12) is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. AUNP-12 exhibits immune activation, excellent antitumor activity, and potential for better management of immune-related adverse events (irAEs)[1]. |
IC50 Target |
PD-1 signaling pathway[1] |
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体外研究 (In Vitro) |
AUNP-12 displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions [1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
3261.55 |
Formula |
C5H17TFIN2O2S2Si |
CAS 号 |
1353563-85-5 |
Sequence Shortening |
H-SNTSESFKF(H-SNTSESF)RVTQLAPKAQIKE-NH2 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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