IGF-I (24-41) (TFA)(Synonyms: Insulin-like Growth Factor I (24-41) (TFA))

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IGF-I (24-41) (TFA);(Synonyms: Insulin-like Growth Factor I (24-41) (TFA))

IGF-I (24-41) (TFA) 是类胰岛素生长因子I 24 至 41 的氨基酸片段。IGF-I 对生长激素的活性有着重要的作用，但是IGF-I本身也具有一些自身的特性，如合成代谢、抗氧化、抗炎和细胞保护作用。

IGF-I (24-41) (TFA)amp;;(Synonyms: Insulin-like Growth Factor I (24-41) (TFA))

IGF-I (24-41) (TFA) Chemical Structure

规格 是否有货
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IGF-I (24-41) (TFA) 的其他形式现货产品:

IGF-I (24-41)

生物活性

IGF-I (24-41) (TFA) is amino acids 24 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions)[1].

分子量

2131.18

Formula

C88H133N27O28.C2HF3O2
Sequence

Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr
Sequence Shortening

YFNKPTGYGSSSRRAPQT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Puche JE, et al. Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med. 2012 Nov 14;10:224.