Mad1 (6-21) (TFA);
Mad1 (6-21) TFA 是 Mad1 蛋白的 6-21 片段。Mad1 (6-21) TFA 与哺乳动物 Sin3A PAH2 结合,Kd 为 ~29 nM。
Mad1 (6-21) (TFA) Chemical Structure
规格 | 是否有货 | ||
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100 mg | ; | 询价 | ; |
250 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
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生物活性 |
Mad1 (6-21) TFA is the 6-21 fragment of Mad1 protein. Mad1 (6-21) TFA binds to mammalian Sin3A PAH2 with a Kd of ~29 nM[1]. |
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体外研究 (In Vitro) |
The PAH2 domain of mSin3A adopts a left-handed, up-and-down, four-helix bundle structure with residues in all four helices as well as in the turn regions defining a compact structural domain with an extensive hydrophobic core. Helices α1 and α2 form a deep hydrophobic pocket, which constitutes the primary interaction surface for the Mad1 (6-21) peptide. The Mad1 (6-21) forms an amphipathic α helix in the complex and interacts with PAH2 mainly through the apolar surface of the helix[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
2080.31 |
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Formula |
C86H141F3N24O28S2 |
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Sequence Shortening |
RMNIQMLLEAADYLER |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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Solvent Solubility |
In Vitro:;
H2O Peptide Solubility and Storage Guidelines: 1.;;Calculate the length of the peptide. 2.;;Calculate the overall charge of the entire peptide according to the following table:
3.;;Recommended solution:
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参考文献 |
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