[Ala17]-MCH TFA

发表于由

[Ala17]-MCH TFA;

[Ala17]-MCH TFA 是一种 MCH (HY-P1525A) 的类似物，是 MCHR1 的配体 (Ki=0.16 nM) 选择性优于对 MCHR2 的 (Ki=34 nM)。Eu3+螯合标记 [Ala17]-MCH 对 MCHR1 (Kd=0.37 nM) 亲和性高，而对 MCHR2 的亲和性低。

[Ala17]-MCH TFAamp;;

[Ala17]-MCH TFA Chemical Structure

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[Ala17]-MCH TFA 的其他形式现货产品:

[Ala17]-MCH

生物活性

[Ala17]-MCH TFA, a MCH analogue (HY-P1525A), is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM). [Eu3+ chelate-labeled [Ala17]-MCH shows high affnity for MCHR1 (Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2[1].

IC50 Target

Ki: 0.16 nM (MCHR1)
Ki: 34 nM (MCHR2)[1]
分子量

2385.73

Formula

C99H156F3N29O28S4
Sequence Shortening

DFDMLRCMLGRVYRPCAQV (Disulfide bridge:Cys7-Cys16)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Xiaoying Gao, et al. Europium-labeled melanin-concentrating hormone analogues: ligands for measuring binding to melanin-concentrating hormone receptors 1 and 2. Anal Biochem. 2004 May 15;328(2):187-95.