Proadrenomedullin (45-92), human

Proadrenomedullin (45-92), human;

Proadrenomedullin (45-92), human 是肾上腺髓质素原 (MR-proADM) 的中间区域片段,包括肾上腺髓质素原前体 (pre-proADM) 的 45-92 个氨基酸。Proadrenomedullin (45-92), human 半衰期更长且相对稳定,与肾上腺髓质素 (ADM) 等摩尔量生成,使其成为肾上腺髓质素基因产物血浆水平的替代指标。

Proadrenomedullin (45-92), humanamp;;

Proadrenomedullin (45-92), human Chemical Structure

CAS No. : 166798-69-2

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生物活性

Proadrenomedullin (45-92), human, a mid-regional fragment of proadrenomedullin (MR-proADM), comprises amino acids 45–92 of pre-proADM. Proadrenomedullin (45-92), human has a longer half-life, is relatively stable and is produced in equimolar amounts to adrenomedullin (ADM), making it a surrogate for plasma levels of ADM gene products[1][2].

分子量

5114.76

Formula

C215H359N67O73S2

CAS 号

166798-69-2

Sequence

Glu-Leu-Arg-Met-Ser-Ser-Ser-Tyr-Pro-Thr-Gly-Leu-Ala-Asp-Val-Lys-Ala-Gly-Pro-Ala-Gln-Thr-Leu-Ile-Arg-Pro-Gln-Asp-Met-Lys-Gly-Ala-Ser-Arg-Ser-Pro-Glu-Asp-Ser-Ser-Pro-Asp-Ala-Ala-Arg-Ile-Arg-Val

Sequence Shortening

ELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRV

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Lorubbio M, et al. Midregional pro-adrenomedullin (MR-ProADM) reference values in serum. Clin Biochem. 2018 Mar;53:173-174.

    [2]. Al-Omari MA, et al. Mid-regional pro-adrenomedullin is associated with pulse pressure, left ventricular mass, and albuminuria in African Americans with hypertension. Am J Hypertens. 2009 Aug;22(8):860-6.