Leptin (116-130)

Leptin (116-130);

Leptin (116-130) 是一种具有生物活性的瘦素片段。Leptin (116-130) 促进 AMPA 受体运输到突触并促进活动依赖性海马突触可塑性。Leptin (116-130) 在淀粉样蛋白毒性模型中防止海马突触破坏和神经元细胞死亡。Leptin (116-130) 具有研究阿尔茨海默病 (AD) 的潜力。

Leptin (116-130)amp;;

Leptin (116-130) Chemical Structure

CAS No. : 189224-35-9

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生物活性

Leptin (116-130) is a bioactive leptin fragment. Leptin (116-130) promotes AMPA receptor trafficking to synapses and facilitate activity-dependent hippocampal synaptic plasticity. Leptin (116-130) prevents hippocampal synaptic disruption and neuronal cell death in models of amyloid toxicity. Leptin (116-130) has the potential for the research of Alzheimer’s disease (AD)[1].

分子量

1561.72

Formula

C₆₄H₁₀₈N₁₈O₂₅S

CAS 号

189224-35-9

Sequence Shortening

SCSLPQTSGLQKPES

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Malekizadeh Y, et al. A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin. Cereb Cortex. 2017;27(10):4769-4782.

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