H3K4(Me) (1-20)

H3K4(Me) (1-20);

H3K4(Me) (1-20) 是一种组蛋白肽,H3K4me 是一种复杂调控的翻译后修饰,与活跃转录的基因组位点的增强子和启动子密切相关。

H3K4(Me) (1-20)amp;;

H3K4(Me) (1-20) Chemical Structure

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生物活性

H3K4(Me) (1-20), a histone peptide. H3K4me is an intricately regulated posttranslational modification, which is broadly associated with enhancers and promoters of actively transcribed genomic loci[1].

分子量

2197.58

Formula

C92H169N35O27

Sequence

Ala-Arg-Thr-{Lys(Me)}-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu

Sequence Shortening

ART-{Lys(Me)}-QTARKSTGGKAPRKQL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mulder KW, et al. Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res. 2007;35(7):2428-2439.

    [2]. Vallianatos CN, et al. Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders. Epigenomics. 2015;7(3):503-519.