CKLF1-C27;
CKLF1-C27 是 CKLF1 的 C 末端肽,与 CCR4 受体结合并激活 ERK1/2 通路。CKLF1-C27 可以通过竞争 CCR4 受体来消除 CKLF1 对细胞的影响。CKLF1-C27对促进HUVECs增殖有很大的作用。CKLF1-C27 具有用于银屑病研究的潜力。
CKLF1-C27 Chemical Structure
CAS No. : 891861-48-6
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生物活性 |
CKLF1-C27, a C-terminal peptide of CKLF1, binds to CCR4 receptor and activates ERK1/2 pathway. CKLF1-C27 can abrogate the effect of CKLF1 on cells by competing for CCR4 receptor. CKLF1-C27 shows great effect on promoting proliferation on HUVECs. CKLF1-C27 has the potential for psoriasis research[1]. |
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IC50 Target[1] |
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分子量 |
3196.78 |
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Formula |
C151H243N39O37 |
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CAS 号 |
891861-48-6 |
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Sequence Shortening |
ALIYRKLLFNPSGPYQKKPVHEKKEVL |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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