Phalloidin-TRITC

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Phalloidin-TRITC;

Phalloidin-TRITC 是TRITC 标记的、红色 F-actin 探针。Phalloidin 结合在肌动蛋白丝上，与氨基酸 Glu-llT、Met-ll9 和 Met355 共价反应，这些氨基酸和核苷酸结合位点非常接近。

Phalloidin-TRITCamp;;

Phalloidin-TRITC Chemical Structure

CAS No. : 915013-10-4

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生物活性

Phalloidin-TRITC is a TRITC labeled, red fluorescence probe for F-actin. Phalloidin, bound to actin filaments, reacts covalently with amino acids Glu-llT, Met-ll9, and Met355, which are very close to the nucleotide binding site[1].

体外研究
(In Vitro)

Phalloidin induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1231.40

Formula

C60H70N12O13S2
CAS 号

915013-10-4
Sequence Shortening

A-{d-Thr}-C-{Hyp}-AW-{Thr} (Covalent bridge:Cys3-Trp6)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. J A Cooper, et al. Effects of cytochalasin and phalloidin on actin. J Cell Biol. 1987 Oct;105(4):1473-8.

    [2]. J Wehland, et al. Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5613-7.