SMAP-29

发表于由

SMAP-29;

SMAP-29，一种有效的抗感染 (antiinfective) 试剂，是广谱抗细菌和抗真菌的螺旋抗菌肽衍生肽。SMAP-29 的作用是通过渗透细菌膜，诱导敏感微生物的表面形态发生显著变化。

SMAP-29amp;;

SMAP-29 Chemical Structure

CAS No. : 172485-26-6

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生物活性

SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism[1][2].

IC50 Target

IC50: bacterial; fungal[1]
分子量

3256.02

Formula

C146H260N52O32
CAS 号

172485-26-6
Sequence Shortening

RGLRRLGRKIAHGVKKYGPTVLRIIRIAG
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. B Skerlavaj, et al. SMAP-29: a potent antibacterial and antifungal peptide from sheep leukocytes. FEBS Lett. 1999 Dec 10;463(1-2):58-62.

    [2]. Rachel C Anderson, et al.Antimicrobial activity and bacterial-membrane interaction of ovine-derived cathelicidins. Antimicrob Agents Chemother